无创胎儿鉴定介绍
无创胎儿鉴定是目前针对孕期怀孕孕妇的最先进高端的鉴定方式。我们现在知道如动图所示,怀孕时母体中胎儿的DNA(Fetal dna)会同步进入孕妇的血液中,因此我们只需要孕妇的手臂静脉血15ml, 利用新一代DNA测序技术对母体外周血中的游离DNA片段(包含胎儿游离DNA)进行测序、生物信息分析,从中得到胎儿的遗传信息,并与假定父亲的样本中的DNA信息进行比对,实现确认关系。
技术原理
无创胎儿鉴定技术选取第三代遗传学标记—单核苷酸多态性(single nucleotide polymorphism,SNP)位点进行检测,使用液相杂交方法富集,通过高通量测序进行基因分型,最后根据孟德尔遗传规律判断疑父和胎儿之间是否存在关系。
对比传统胎儿鉴定的优势
样本要求
- 女方:手臂静脉血15ML 使用专用无创试管采集
蕴亲优势
- 遗传咨询和生信分析团队;
- 标准化医学检验所和规范化的操作流程;
- 先进的Illumina 测序设备;
- 检测40000个SNP位点;
- 依据国家最新《亲权鉴定技术规范》,结果精准可靠;
- 全方位服务,专人全程对接。
鉴定费用 官方报价
鉴定取报告时间
最晚五个工作日内可得到鉴定报告。
无创胎儿鉴定也是DNA鉴定的一种,因为是属于早期的鉴定,技术要求很高。目前国内真正掌握该项技术的很少。
我们重视对每一位委托人隐私的保护,用于鉴定的样本全程处于保护监控状态,结果也不接受其他任何部门及个人查询,无须担心个人隐私的暴露。
无创产前鉴定尤其适用人群:
1、由于心理压力大,不愿承受侵入性取样的孕妇
2、由于胎盘前置、孕囊低置或羊水过少而不宜接受侵入性取样的孕妇
3、孕周6周及以上的单胎孕妇
4、年龄达35岁及以上的高龄孕妇
5、有其他特殊情况及要求的人群
不适于做无创鉴定的情况
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近一年内接受过异体输血的孕妇
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接受过器官移植手术、干细胞治疗等的孕妇
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4周之内接受过引入外源DNA的免疫治疗的孕妇
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怀有多胞胎(双胞胎及以上)的孕妇
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做过减胎手术的孕妇
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患有先兆子痫或肿瘤疾病的孕妇
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